Anchor Therapeutics is seeking motivated individuals to join our team in Cambridge, Massachusetts. We are pioneering a new class of drugs targeting GPCRs and are looking for a highly motivated and talented scientists. The successful candidate should have a strong scientific background and the desire to make a positive impact in a growing biotechnology company.

Please send your resume and cover letter to careers@anchortx.com; please include job code for postings in the subject line.

Project Manager (Job Code: PM/SH)

The Project Manager will be responsible for managing a portfolio of Anchor Therapeutics’ internal projects and projects contained within external partner collaborations.  In addition, the Project Manager will establish and oversee relationships with external academic collaborators, contract research organizations and suppliers.  The Project Manager will also assist in writing grants to federal agencies and private foundations and manage awarded grants.  This position is being recruited at the Associate Director/Director level and will report to the CSO/SVP R&D.  Specific responsibilities include:

• Define project goals and deliverables with Project Leaders, management, and relevant stakeholders.
• Develop project strategy, plans, responsibilities and timelines with Project Teams.
• Identify functions and estimate resources required for project prosecution with Project Teams.
• Establish budget, propose revisions, and oversee project spending.
• Identify needs for additional or specialized staff/consultants and make recommendations to management.
• Plan and track project progress, milestones, and deliverables using appropriate software tools.
• Anticipates crises/deficiencies and creates contingency plans to address.
• Schedule, plan, and summarize Project Team meetings including follow-up on action items.
• Create and deliver project progress reports, presentations, and milestone transition documents.
• Communicate with Project Teams and management.
• Identify and resolve issues and conflicts within the Project Team.

Requirements:

• Minimum BS/MS in scientific discipline.
• 5-7 years direct work experience in drug discovery/development project management.
• Experience managing multi-party collaborations.
• Hands-on experience with relevant project management software programs.
• Proficiency working in a team-oriented, collaborative environment.
• Excellent organizational skills.
• Ability to change course (priorities, timelines, and resources) in response to changing environment.
• Excellent written and oral communication skills.
• Strong interpersonal skills.
• Grant writing experience highly desirable.

Senior Scientist in Mechanistic Biology (Job Code: S/JJ)

The successful candidate will work with the Biology group and lead efforts designed to further our understanding of pepducin mechanisms of action.  The candidate will be responsible for designing, developing and applying in vitro assays to characterize the pharmacological and biophysical properties of lipidated peptides.  He/she will lead investigations exploring the interface between lipidated peptides and cellular membranes and integral membrane proteins.    The successful candidate, in addition to other research endeavors, will direct a research program investigating the insertion and distribution of lipidated peptides in cellular membranes.  As such, he/she should possess strong working knowledge of peptide, lipid and membrane biology.  He/she should be an effective, self-motivated, and creative scientist capable of independently executing, analyzing, and troubleshooting experiments.  The position requires excellent oral and written communication skills as well as strong organizational and critical thinking skills.  The successful candidate should function well in a group setting and be an active contributor to both the biology and chemistry groups. 

The position requires a strong applied background in biochemical and biophysical techniques typically associated with a Ph.D. in biochemistry, biophysics or a similar filed.   Experienced MS level scientists will also be considered.  Experience working with cellular membranes and membrane proteins is essential.  The ideal candidate will also have a strong understanding of lipid biochemistry and be able to apply this knowledge in the development of lipidated peptide therapeutics.  Experience with molecular modeling and molecular dynamics (MD) simulations is preferred.  Experience with advance biochemical and biophysical techniques including CD, FTIR, ITC, DSC, HPLC and NMR is desirable.  

Associate Scientist in In Vitro Pharmacology (Job Code: AS/YR)

The successful candidate should hold a BS or MS degree in Biology or related science and at least two years experience in a drug discovery setting.  The candidate will be responsible for conducting in vitro assays for screening and characterizing compounds, and for analyzing and presenting data as part of a drug development project team.  He/she should be an effective and creative scientist capable of independently executing, analyzing, and troubleshooting experiments.  The position requires excellent oral and written communication skills as well as strong organizational and critical thinking skills. 

Proficiency in data analysis software (Excel, GraphPad prism) is required.  Post graduate experience in mammalian cell culture, cell-based and cell-free GPCR assays (calcium, cAMP, receptor binding), is absolutely required.  Experience in robotic liquid handling, FACS analysis, and data management software is strongly preferred.